Framed family photographs show Wendy Nelson with her sisters and their parents, as well as her three children, in the foyer of her home in Foxborough, Massachusetts, U.S., March 21, 2023. Wendy Nelson’s mother died from Alzheimer’s disease, her father suffers from it, and genetic tests show that Wendy carries two APOE4 gene variants, and her three daughters each carry one APOE4 gene variant, indicating an increased risk of Alzheimer’s disease. REUTERS/Brian Snyder