BEIJING (AP) — Asian stocks sank again Friday after German inflation spiked higher, British Prime Minister Liz Truss defended a tax-cut plan that rattled investors and Chinese manufacturing weakened.

Shanghai, Tokyo, Hong Kong and Sydney retreated. Oil prices edged lower.

Wall Street’s benchmark S&P 500 index fell 2.1% on Thursday to its lowest level in almost two years after strong U.S. jobs data reinforced expectations the Federal Reserve will stick to plans for more interest rate hikes.

Investors increasingly worry the global economy might tip into recession following interest rate hikes by the Fed and central banks in Europe and Asia to cool inflation that is at multi-decade highs. Global export demand is weakening and Russia’s attack on Ukraine has disrupted oil and gas markets.

Markets slipped Thursday after Germany reported September inflation accelerated to 10.9% and Chancellor Olaf Scholz said the world’s fourth-biggest economy faces a “double whammy” as energy prices surge.

“We’d be inclined to argue that we haven’t yet seen the bottom,” said ING economists in a report.

The Shanghai Composite Index lost 0.6% to 3,023.91 after surveys of manufacturers showed production and new orders declined in September.

The Nikkei 225 in Tokyo fell 1.7% to 25,979.75 and the Hang Seng in Hong Kong declined by 0.2% to 17,126.01. The Kospi in Seoul added 0.2% to 2,173.71.

Sydney’s S&P ASX 200 sank 0.7% to 6,506.20. New Zealand and Southeast Asian markets declined.

Investors already were uneasy about signs global activity was weakening before Truss’s government announced multibillion-dollar tax cuts. Traders worry that will push up already high inflation, forcing the British central bank to cool economic growth by raising interest rates further.

Stock markets and the value of the British pound rebounded Wednesday after the Bank of England said it would buy government bonds to support their price. But markets resumed their slide Thursday after Truss shrugged off criticism and defended her tax-cut plan despite a plea from the International Monetary Fund to reverse course.

On Wall Street, the S&P 500 fell to 3,640.47. More 90% of the stocks in the index declined, putting it on track to end September with an 8% loss for the month.

The Dow Jones Industrial Average fell 1.5% to 29,225.61 and the Nasdaq composite lost 2.8% to 10,737.51.

The S&P 500 is down more than 20% for the year as investors wait for a break in inflation that has prompted the Fed to raise interest rates five times.

The yield on a two-year U.S. Treasury, or the difference between its market price and the payout at maturity, widened to 4.2% from Wednesday’s 4.14%.

Stronger than expected U.S. employment data Thursday reinforced expectations the Fed will feel comfortable sticking to plans to raise interest rates further and keep them elevated through next year.

Fewer workers filed for unemployment benefits last week than forecast.

In China, surveys of manufacturers by business news magazine Caixin found production and news orders declined. That was in line with expectations that a Chinese manufacturing boom would fade due to weak global demand.

The Caixin monthly purchasing managers’ index declined from its August level while a separate index by the China Federation of Logistics & Purchasing edged above a break-even point that shows activity increasing.

“The downturn in external demand looks set to deepen,” said Zichun Huang of Capital Economics in a report.

In energy markets, benchmark U.S. crude lost 9 cents to $81.14 per barrel in electronic trading on the New York mercantile Exchange. The contract fell 92 cents Thursday to $81.23. Brent crude, used to price international oils, shed 10 cents to $87.08 per barrel in London. It lost 83 cents the previous session to $88.49.

The dollar rose to 144.70 yen from Thursday’s 144.43 yen. The euro rose to 98.05 cents from 97.90 cents.